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Arizona Cardinals vs San Francisco 49ers Predictions & Picks

One of the most anticipated matches in NFL round five this weekend is taking place on Sunday afternoon at State Farm Stadium where Arizona Cardinals welcome San Francisco 49ers. The Niners and their fans were definitely hoping for a better start than two wins and two defeats record, but truth be told, the schedule was extremely hard. Read on our betting picks and predictions below.

Arizona Cardinals vs San Francisco 49ers Predictions

October 10th 2021 – 4:25 ET


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Tip Reasoning

  • Can Arizona Cardinals be serious Super Bowl contender this year?
  • They have opened the new season with four victories in a row and scored a lot of points
  • SF 49ers are discouraged by last weekend’s home loss to Seattle Seahawks

Hosts are ranked as top team in the league in many offense categories

It is hard to tell if people should be surprised with the fact that Arizona Cardinals opened this brand new season with four consecutive victories. Team has been on the rise for years now, and we see them as very serious contender at least for the Conference finals. In terms of the lines, betting sites in New Jersey have marked hosts as team closer to claim win, currently favored by 5.5 points. All their victories so far have been amazing, but we were completely impressed by last weekend’s performance against Los Angeles Rams, beating the opposition 37:20. Kyler Murray is playing out of his mind so far, completing 76% of passes for 1,273 yards total! He has nine touchdown passes, but also four turnovers. There is no doubt whole team will be motivated to perform well in front of the home crowd after playing three duels on the road. Cardinals are topping league’s charts for total offense and scoring offense, so we have no other choice but to back them in -5.5 spread betting.

Game Totals Prediction

Picking the Over 50.5 points total was an easy choice. Cardinals have scored over 30 points in every single match played this season.

Q. What time is Cardinals v 49ers game starts?

Sunday 4:25 ET

Q. What ground is the Cardinals v 49ers played at?

State Farm Stadium

Q. What are the odds on Cardinals winning?

-233 (Odds subject to chance)

Q. What are the odds on 49ers winning?

+193 (Odds subject to change)

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